Dopamine and insulin interact in the brain to control junk food cravings. These findings provide evidence that disruptions in this delicate balance make it harder to resist sugary and fatty foods, even when eating them has negative consequences.

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Deborah Alsina, chief executive of Arthritis UK, said: "This is a crushing blow for those individuals who have finally made it to the front of the orthopaedic surgery queue after a long time waiting.

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